abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:Human papilloma virus (HPV) infection is a precursor of cervical cancer. This study aimed to introduce a method to quantify the risk of cervical cancer resulting from infection by different HPV subtypes, to help guide patient treatment. Nucleic acid molecule flow-through hybridization and gene chip technology were use...

journal_title：Journal of medical virology

authors： Zhu X,Liu H,Wu H,Liu W,Yin L,Sun X

更新日期：2015-12-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised individuals and is recognized as a major viral cause of birth defects. HCMV has the ability to establish lifelong persistence and latent infection following primary exposure. Apoptosis is an innate cellular defense response to vir...

journal_title：Journal of medical virology

authors： Li HP,Yuan CL,Zho YC

更新日期：2015-11-01 00:00:00

abstract：:Human bocavirus (HBOV) has been reported as a worldwide distributed respiratory pathogen. It has also been associated with encephalitis recently by detection of the virus in cerebrospinal fluid (CSF) of patients presented with encephalitis. This retrospective study aimed to present clinical features of HBOV infections...

journal_title：Journal of medical virology

authors： Akturk H,Sık G,Salman N,Sutcu M,Tatli B,Ciblak MA,Erol OB,Torun SH,Citak A,Somer A

更新日期：2015-11-01 00:00:00

abstract：:West Nile virus (WNV) activity has fluctuated in the south-central United States since its introduction. Seasonal outbreaks are common, with three in Oklahoma during 2003, 2007, and 2012. Morbidity and mortality rates vary during each outbreak. Long-term neurologic sequelae in association with West Nile virus disease ...

journal_title：Journal of medical virology

authors： Johnson MG,Adams J,McDonald-Hamm C,Wendelboe A,Bradley KK

更新日期：2015-10-01 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of hepatitis B e antigen (HBeAg) negative/treatment naïve subjects with low hepatitis B virus (HBV) DNA levels (<10(4)  copies/ml) and low alanine aminotransferase (ALT) levels (<2 × upper limit of normal) in patients with HBV-related hepatocellular carcinoma (HCC)....

journal_title：Journal of medical virology

authors： Zeng DW,Dong J,Zhang JM,Zhu YY,Jiang JJ,Liu YR

更新日期：2015-10-01 00:00:00

abstract：:High risk types of human papillomaviruses E6/E7 oncogenes and their association with tumor suppressor genes products are the key factors of cervical carcinogenesis. This study proposed them as specific markers for cervical dysplasia screening. The aim of the study is to compare the clinical and prognostic significance...

journal_title：Journal of medical virology

authors： Duvlis S,Popovska-Jankovic K,Arsova ZS,Memeti S,Popeska Z,Plaseska-Karanfilska D

更新日期：2015-09-01 00:00:00

abstract：:The presence of therapy-associated hepatitis B virus (HBV) variants is the main drawback of antiviral therapy for HBV infection. Moreover, drug-resistant variants are more insensitive to a second agent and more therapy-associated mutations will be present. To apply better nucleos(t)ide analogues (NA) and reduce the oc...

journal_title：Journal of medical virology

authors： Su F,Dai J,Yang S,Jiang X,Cui X,Ning H,Li J,Huang M

更新日期：2015-09-01 00:00:00

abstract：:The number of new HIV diagnoses is increasing in the western world and transmission clusters have been recently identified among men having sex with men despite Highly Active Antiretroviral Therapy efficacy. The objective of this study was to assess temporal trends, epidemiological, clinical and virological characteri...

journal_title：Journal of medical virology

authors： Tamalet C,Ravaux I,Moreau J,Brégigeon S,Tourres C,Richet H,Abat C,Colson P

更新日期：2015-08-01 00:00:00

abstract：:The impact of dynamic respiratory syncytial virus (RSV) load on the clinical severity of hospitalized infants with bronchiolitis has not been clarified. Nasopharyngeal aspirates were obtained from 60 infants who were diagnosed with bronchiolitis within 96 hr of wheezing onset upon admission and on days 3, 5, and 7 in ...

journal_title：Journal of medical virology

authors： Zhou L,Xiao Q,Zhao Y,Huang A,Ren L,Liu E

更新日期：2015-08-01 00:00:00

abstract：:The human parvovirus B19 (B19) usually causes a subclinical infection in immunocompetent individuals. Whereas immunocompromised individuals such as patients infected with HIV are at risk of persistent anemia due to B19 infection. Only few studies have been carried out on distribution and molecular epidemiology of B19 ...

journal_title：Journal of medical virology

authors： Azadmanesh K,Mohraz M,Kazemimanesh M,Aghakhani A,Foroughi M,Banifazl M,Eslamifar A,Ramezani A

更新日期：2015-07-01 00:00:00

abstract：:Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by other parechoviruses is not ruled out. The aim was to compare children diagnosed with type 1 diabetes in 2005-2011 (n = 69) with healthy controls (n = 294), all from the Jämtland County in Sweden, usin...

journal_title：Journal of medical virology

authors： Nilsson AL,Vaziri-Sani F,Broberg P,Elfaitouri A,Pipkorn R,Blomberg J,Ivarsson SA,Elding Larsson H,Lernmark Å

更新日期：2015-07-01 00:00:00

abstract：:Previous investigations of fomite transmission have focused on the presence of pathogens on inanimate objects in clinical settings. There has been limited investigation of fomite transmission in non-clinical pediatric settings where there is a high prevalence of respiratory virus infections. Over a 5 week period, this...

journal_title：Journal of medical virology

authors： Gralton J,McLaws ML,Rawlinson WD

更新日期：2015-06-01 00:00:00

abstract：:Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analog...

journal_title：Journal of medical virology

authors： Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV

更新日期：2015-06-01 00:00:00

abstract：:Hantaviruses is an emerging infectious disease. Although HCPS has been reported in several regions of Brazil, more cases of HCPS have recently been reported in Minas Gerais than in any other state. In 2009, we analyzed 27 samples presenting antibodies against hantaviruses. These samples originated from 688 symptomatic...

journal_title：Journal of medical virology

authors： de Araujo J,Duré AI,Negrão R,Ometto T,Thomazelli LM,Durigon EL

更新日期：2015-05-01 00:00:00

abstract：:Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were...

journal_title：Journal of medical virology

authors： Carmona-Vicente N,Fernández-Jiménez M,Ribes JM,Téllez-Castillo CJ,Khodayar-Pardo P,Rodríguez-Diaz J,Buesa J

更新日期：2015-04-01 00:00:00

abstract：:Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

journal_title：Journal of medical virology

authors： Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

更新日期：2015-03-01 00:00:00

abstract：:HCV strains belonging to genotype 4 may be gaining endemicity across Continental Europe but the extent of their spread in the United Kingdom is unknown. Sera referred from patients attending hospitals in England between 2004 through 2008 were characterised. A total of 243 sera carried HCV genotype 4. The most common s...

journal_title：Journal of medical virology

authors： Ngui SL,Brant L,Markov PV,Tung JP,Pybus OG,Teo CG,Ramsay ME

更新日期：2015-03-01 00:00:00

abstract：:The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...

journal_title：Journal of medical virology

authors： El Shazly Y,Hemida K,Rafik M,Al Swaff R,Ali-Eldin ZA,GadAllah S

更新日期：2015-03-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

journal_title：Journal of medical virology

authors： Ren L,Xiao Q,Zhou L,Xia Q,Liu E

更新日期：2015-01-01 00:00:00

abstract：:Enteroviruses (EVs) often infect humans, presenting as endemic or epidemic infections. In this study, the diversity of infecting EVs was studied among 146 children and 137 adults in a small community in Cameroon. The participants provided 2,458 fecal samples during 1-year monthly collection; 10 or more samples were ob...

journal_title：Journal of medical virology

authors： Ayukekbong JA,Fobisong C,Lindh M,Nkuo-Akenji T,Bergström T,Norder H

更新日期：2014-12-01 00:00:00

abstract：:Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...

journal_title：Journal of medical virology

authors： Zhu Z,Chen MH,Abernathy E,Zhou S,Wang C,Icenogle J,Xu W

更新日期：2014-12-01 00:00:00

abstract：:Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 ch...

journal_title：Journal of medical virology

authors： Ahn JG,Choi SY,Kim DS,Kim KH

更新日期：2014-12-01 00:00:00

abstract：:The question of whether booster doses are required to maintain long-term protection against hepatitis B virus (HBV) after primary vaccination remains to be determined. Thus, the aim of this study was to evaluate the immune memory responses to hepatitis B surface antigen (HBsAg) challenge in vaccinated individuals thro...

journal_title：Journal of medical virology

authors： do Livramento A,Schultz J,Batista KZ,Treitinger A,de Cordova CM,Spada C

更新日期：2014-10-01 00:00:00

abstract：:The present study compared the efficacy of standard and extended durations of PEG-IFNα-2a monotherapy for treatment of HBeAg-negative Chinese patients with chronic hepatitis B. Patients were randomized to receive standard therapy (n = 38; 48 weeks treatment) or extended therapy (n = 42; 72 weeks treatment). Extended t...

journal_title：Journal of medical virology

authors： Chen X,Chen X,Chen W,Ma X,Huang J,Chen R

更新日期：2014-10-01 00:00:00

abstract：:Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...

journal_title：Journal of medical virology

authors： Cai J,Lv H,Lin J,Chen Z,Fang C,Han J

更新日期：2014-09-01 00:00:00

abstract：:Occult hepatitis C virus (HCV) infection is characterized by the presence of HCV RNA in the liver cells or peripheral blood mononuclear cells of the patients whose serum samples test negative for HCV RNA, with or without presence of HCV antibodies. The present study reviews the existing literature on the persistence o...

journal_title：Journal of medical virology

authors： Vidimliski PD,Nikolov I,Geshkovska NM,Dimovski A,Rostaing L,Sikole A

更新日期：2014-09-01 00:00:00

abstract：:JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Cz...

journal_title：Journal of medical virology

authors： Sroller V,Hamšíková E,Ludvíková V,Vochozková P,Kojzarová M,Fraiberk M,Saláková M,Morávková A,Forstová J,Němečková S

更新日期：2014-09-01 00:00:00

abstract：:Enterovirus 68 (EV-D68) was associated with mild to severe respiratory infections. In the last 4 years, circulation of different EV-D68 strains has been documented worldwide. In this study, the phylogenetic characterization of nine EV-D68 strains identified in patients in the 2010-2012 period and 12 additional EV-D68 ...

journal_title：Journal of medical virology

authors： Piralla A,Girello A,Grignani M,Gozalo-Margüello M,Marchi A,Marseglia G,Baldanti F

更新日期：2014-09-01 00:00:00

abstract：:Human herpes virus 8 (HHV 8) is recognized as the necessary cause of Kaposi sarcoma (KS) and in the recent past the human papillomavirus (HPV) has been linked to the development of cutaneous basal cell and squamous cell carcinomas. In a cross sectional study investigating Beta-HPV infections in skin lesions, an unexpe...

journal_title：Journal of medical virology

authors： Murahwa AT,Muchemwa FC,Duri K,Borok MZ,Kanyera RB,Manhanzva MT,Mapingure MP,Stray-Pedersen B

更新日期：2014-09-01 00:00:00

abstract：:Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda-3 (IFNL3 or IL-28B) and IFNL4 genes and treatment response to hepatitis C virus genotype 1 (HCV-1) infection. The importance of these SNPs for HCV genotype 3 (HCV-3), and particularly HCV genotype 6 (HCV-6)...

journal_title：Journal of medical virology

authors： Akkarathamrongsin S,Thong VD,Payungporn S,Poovorawan K,Prapunwattana P,Poovorawan Y,Tangkijvanich P

更新日期：2014-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) has infected approximately 170 million people worldwide. While the seroprevalence of anti-HCV antibody among Iranian blood donors is 0.13%, HCV infection is prevalent in 59-80% of Iranian injecting drug users. One hundred seventy-eight anti-HCV positive patients were referred to the Gastroenter...

journal_title：Journal of medical virology

authors： Salehi Moghadam F,Mohebbi SR,Hosseini SM,Romani S,Mirtalebi H,Azimzadeh P,Damavand B,Naghoosi H,Khanyaghma M,Sanati A,Zali MR

更新日期：2014-08-01 00:00:00

abstract：:Enterovirus infections are usually mild but can also cause severe illnesses and play a role in chronic diseases, such as cardiomyopathies and type 1 diabetes. Host response to the invading virus can markedly modulate the course of the infection, and this response varies between individuals due to the polymorphism of i...

journal_title：Journal of medical virology

authors： Hämäläinen S,Nurminen N,Ahlfors H,Oikarinen S,Sioofy-Khojine AB,Frisk G,Oberste MS,Lahesmaa R,Pesu M,Hyöty H

更新日期：2014-08-01 00:00:00

abstract：:Pregnant women are not screened for HBsAg and anti-HCV antibodies in many African countries. As there are few data concerning the prevalence of HBV, HDV, and HCV serological markers in Benin, the aim of this study was to evaluate their 2011 prevalence in pregnant women undergoing HIV screening in a rural area of north...

journal_title：Journal of medical virology

authors： De Paschale M,Ceriani C,Cerulli T,Cagnin D,Cavallari S,Ndayaké J,Zaongo D,Priuli G,Viganò P,Clerici P

更新日期：2014-08-01 00:00:00

abstract：:Passively administered antibodies to conserved epitopes on the attachment (G) glycoprotein of human respiratory syncytial virus (hRSV) have potential in the immunoprophylaxis of human infections. This study set out to generate monoclonal antibodies (MAbs) recognizing all prevalent lineages of HRSV and capable of immun...

journal_title：Journal of medical virology

authors： Robinson MJ,Tan CS,Fenwick F,Chambers CJ,Routledge EG,Toms GL

更新日期：2014-07-01 00:00:00

abstract：:Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...

journal_title：Journal of medical virology

authors： Sullivan SG,Komadina N,Grant K,Jelley L,Papadakis G,Kelly H

更新日期：2014-06-01 00:00:00

abstract：:Influenza A/H3N2 viruses are associated with severe epidemics. Antiviral resistance and continued antigenic drift are the major concerns regarding prophylaxis and treatment of influenza. The objectives of this study were to investigate the prevalence and frequency of antiviral drug resistance in influenza A/H3N2 virus...

journal_title：Journal of medical virology

authors： Cai J,Wang X,Zhao B,Yao W,Wang X,Zhu Q,Zeng M

更新日期：2014-06-01 00:00:00

abstract：:The discovery of autochthonous hepatitis E in industrialized countries associated to genotype 3 has changed substantially the understanding about hepatitis E virus (HEV) circulation. In these countries transmission has been associated to the consumption and direct contact to swine, a well-known reservoir for HEV. More...

journal_title：Journal of medical virology

authors： Mesquita JR,Valente-Gomes G,Conceição-Neto N,Nascimento MS

更新日期：2014-06-01 00:00:00

abstract：:Infection with oncogenic human papillomavirus (HPV) genotypes is necessary for the development of cervical cancer. Testing for HPV DNA from liquid based cervical samples can be used as an adjunct to traditional cytological screening. In addition there are ongoing viral load, genotyping, and prevalence studies. Therefo...

journal_title：Journal of medical virology

authors： Brestovac B,Wong ME,Costantino PS,Groth D

更新日期：2014-04-01 00:00:00